My understanding of this issue is just what the grocery stores and manufacturers of pre-packaged meats explain. With all the extra moisture in the meat, the local grocery store also advertises that it is near-impossible to overcook their pork. And, I have found that to be true. I have had plenty of pre-pack meats, and plenty of fresh cut meats as well. On the whole, I have not tasted a palatable difference. The only thing that I do not care for is prepack hamburger. It is packed with a gas in the package that keeps the meat with a longer shelf life, and to give it a look as fresh as fresh-ground hamburger. I don't like the smell of pre-pack hamburger, however, I haven't noticed much of a taste difference. But the smell alone is enough to make me want to go with fresh grind or the hamburger tubes. BTW, I am married to a butcher.