From the experience of contesting a charge with Amex and Visa, the customer support was SO much better with Amex that I would not use Visa again for any purchase unless I have no choice. The hoops Visa asked us to go through (everything had to be faxed or snail-mailed; email was not an acknowledged form of correspondence. Well great, if only we had a viable fax machine at home). Incidentally, this past Small Business Saturday, the owner of a tiny wine boutique on Long Island told me that, though in the past it was true that Amex charged businesses more than the other CC's for transactions, they now all charge the same. And no, I don't work for Amex, nor do any friends or family.