Continuing our look at line extensions of popular over-the-counter products, we turn our gaze to Systane — a leading brand of eye drops.
Here are two of their lubricating eye drop products:

The product on the left is regular Systane “long lasting,” while the one on the right is Systane Ultra “high performance.” Based on its name and description, Systane Ultra seems to be a premium product offering “extended protection.”
A check of the active ingredients of both products, however, reveals a surprise.
*MOUSE PRINT:

Both regular Systane and Systane Ultra have exactly the same active ingredients and seemingly in the same strength! So is this just another marketing gimmick like the one we spotlighted where regular Aleve and Aleve Back & Muscle have identical active ingredients?
We asked Alcon, the maker of Systane, what the actual difference is between these two products, and why they sell two different products with the exact same active ingredients.
A spokesperson for the company explained that the secret is primarily in the inactive ingredients which differ slightly between the two products. According to her that is why the “Ultra” product performs better.
“Compared to Systane, Systane Ultra has a unique mechanism of action due to the inclusion of sorbitol, which serves to optimize the viscosity of the drop to minimize blur by delaying the cross-linking of other inactive ingredients until the drop is actually in the eye. The way the inactive ingredients cross-link once Systane Ultra is dropped into the eye results in the creation of a viscoelastic protective layer over the ocular surface that reduces friction and is maintained between blinks for prolonged ocular comfort. Finally, the interaction of Systane Ultra with natural components of the tear film (e.g., calcium, zinc, and magnesium) strengthens the cross-linking of the protective layer and prolongs retention of the active ingredients on the ocular surface.” –Alcon spokesperson.
Got that?
Given that the “Ultra” product is nearly 50% more expensive, does it then last 50% longer than their regular one? The company didn’t answer that question.
Who would have suspected that two products with identical active ingredients would function differently because of the inactive ingredients? And that poses a problem for label readers who would not be able to glean that fact simply by examining a product’s contents.


